Development and Evaluation of a New Lateral Flow Immunoassay for Serodiagnosis of Human Fasciolosis
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چکیده
منابع مشابه
Development and Evaluation of a New Lateral Flow Immunoassay for Serodiagnosis of Human Fasciolosis
BACKGROUND Human fasciolosis is a re-emerging disease worldwide and is caused by species of the genus Fasciola (F. hepatica and F. gigantica). Human fasciolosis can be diagnosed by classical coprological techniques, such as the Kato-Katz test, to reveal parasite eggs in faeces. However, although 100% specific, these methods are generally not adequate for detection of acute infections, ectopic i...
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An assay device for the rapid detection of Leptospira-specific immunoglobulin M (IgM) antibodies in human sera is presented. The sensitivity (85.8%) and specificity (93.6%) of the assay compared well (91.9% agreement) with those of an IgM enzyme-linked immunosorbent assay routinely used in the serodiagnosis of leptospirosis. The sensitivity of the assay varied with the stage of the disease. The...
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Various serological techniques including immunoprecipitation, indirect haemagglutination and the indirect fluorescence antibody test have been successfully applied for the detection of fasciolosis, mainly in experimental infections. Recently, the most frequently used assay is the ELISA technique with somatic or excretory-secretory antigens obtained from adult flukes. Further purification of suc...
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ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2011
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0001376